Recombinant Human CCL13/MCP-4 Protein (RPCB1469)
- SKU:
- RPCB1469
- Size:
- 10µg
- Tag:
- No tag
- Reactivity:
- Human
- Expression Host:
- Pichia
Description
| Product Name: | Recombinant Human CCL13/MCP-4 Protein |
| SKU: | RPCB1469 |
| Size: | 10µg |
| Tag: | No tag |
| Reactivity: | Human |
| Expression Host: | Pichia |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human CCL13/MCP-4 Protein , tested reactivity inPichiaand has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | <0.1EU/μg |
| Purity: | > 95% by SDS-PAGE. |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Gene ID: | 6357 |
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family chemokine that is chemoattractant for eosinophils, basophils, monocytes, macrophages, immature dendritic cells, and T cells, and its capable of inducing crucial immuno-modulatory responses through its effects on epithelial, muscular and endothelial cells. Similar to other CC chemokines, CCL13 binds to several chemokine receptors (CCR1, CCR2 and CCR3), allowing it to elicit different effects on its target cells. A number of studies have shown that CCL13 is involved in many chronic inflammatory diseases, in which it functions as a pivotal molecule involved in the selective recruitment of cell lineages to the inflamed tissues and their subsequent activation. MCP-4/CCL13 is secreted from chondrocytes and activates the proliferation of rheumatoid synovial cells, thereby leading to joint destruction in RA.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | Q99616 |
 | Recombinant Human CCL13/MCP-4 Protein was determined by SDS- PAGE with Coomassie Blue, showing a band at 10-15 kDa. |
Related Products
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Human MCP-4/CCL13 (Monocyte Chemotactic Protein 4) CLIA Kit (HUES00670)
