Recombinant Human ADGRE5 Protein (His Tag) (RPES8294)
- SKU:
- RPES8294
- Size:
- 20μg
- Tag:
- C-His
- Reactivity:
- Human
- Expression Host:
- Mammalian
- Accession:
- P48960
Description
| Product Name: | Recombinant Human ADGRE5 Protein (His Tag) |
| SKU: | RPES8294 |
| Size: | 20μg |
| Tag: | C-His |
| Reactivity: | Human |
| Expression Host: | Mammalian |
| Accession: | P48960 |
| Sequence: | Gln21-Leu530 |
| Calculated Molecular Weight: | 55.9 kDa |
| Observed Molecular Weight: | 80-100 kDa |
| Synonyms: | ADGRE5, Adhesion G protein-coupled receptor E5, CD 97, CD_antigen=CD97, CD97, CD97 antigen, CD97 antigen subunit beta, CD97 molecule, CD97, Leukocyte antigen CD97, Seven span transmembrane protein, Seven transmembrane helix receptor, Seven transmembrane heterodimeric receptor associated with inflammation, TM7LN 1, TM7LN1 |
| Endotoxin: | < 1.0 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with an 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with an other EGF-TM7 genes on the short arm of chromosome 19.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
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