The RBM15B Polyclonal Antibody (CAB9873) is a highly specific and sensitive tool for researchers studying RBM15B, a protein involved in RNA processing and alternative splicing. This antibody, raised in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the RBM15B protein, this antibody enables the detection and analysis of RBM15B in a variety of cell types, making it an ideal choice for studies in molecular biology and cancer research.RBM15B, also known as RNA-binding protein 15B, plays a crucial role in post-transcriptional gene regulation by modulating the splicing of mRNA transcripts.
Dysregulation of RBM15B has been implicated in various diseases, including cancer and developmental disorders. Therefore, understanding the function and regulation of RBM15B is essential for uncovering its potential therapeutic implications in these pathological conditions.Overall, the RBM15B Polyclonal Antibody provides researchers with a valuable tool to explore the role of RBM15B in RNA processing and disease pathogenesis, ultimately contributing to the development of novel diagnostic and therapeutic strategies in the field of molecular biology and oncology.
Product Name:
RBM15B Rabbit Polyclonal Antibody
SKU:
CAB9873
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 540-720 of human RBM15B (NP_037418.3).
Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).
Purification Method:
Affinity purification
Gene ID:
29890
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RBM15B Antibody (CAB9873) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
