RASD1 Rabbit Polyclonal Antibody (CAB15451)
- SKU:
- CAB15451
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | RASD1 Rabbit Polyclonal Antibody |
SKU: | CAB15451 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 132-281 of human RASD1 (NP_057168.1). |
Sequence: | TKEN VDVP LVIC GNKG DRDF YREV DQRE IEQL VGDD PQRC AYFE ISAK KNSS LDQM FRAL FAMA KLPS EMSP DLHR KVSV QYCD VLHK KALR NKKL LRAG SGGG GGDP GDAF GIVA PFAR RPSV HSDL MYIR EKAS AGSQ AKDK ERCV IS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | AGS1; DEXRAS1; MGC:26290; RASD1 |
Positive Sample: | A-549,LO2,293T,Mouse brain,Mouse heart,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Cytoplasmic side, Lipid-anchor, Nucleus, perinuclear region. |
Calculated MW: | 32kDa |
Observed MW: | 31kDa |
This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 51655 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |