RAB7 Rabbit Monoclonal Antibody (CAB12308)
- SKU:
- CAB12308
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | RAB7 Rabbit Monoclonal Antibody |
SKU: | CAB12308 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 108-207 of human RAB7 (NP_004628.4). |
Sequence: | IQAS PRDP ENFP FVVL GNKI DLEN RQVA TKRA QAWC YSKN NIPY FETS AKEA INVE QAFQ TIAR NALK QETE VELY NEFP EPIK LDKN DRAK ASAE SCSC |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | RAB7; CMT2B; PRO2706 |
Positive Sample: | HeLa,A549,RD,Mouse kidney,Mouse heart,Rat liver,Rat lung,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic side, Cytoplasmic vesicle, Late endosome membrane, Lipid droplet, Lysosome membrane, Melanosome membrane, Peripheral membrane protein, autophagosome membrane, phagosome membrane. |
Calculated MW: | 23kDa |
Observed MW: | 23kDa |
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
Purification Method: | Affinity purification |
Gene ID: | 7879 |
Clone Number: | ARC54437 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |