The Rab4a Rabbit Monoclonal Antibody (CAB3979) is a powerful tool for researchers studying Rab4a, a key regulator of intracellular membrane trafficking. This antibody, developed using rabbit monoclonal technology, demonstrates high specificity and sensitivity in detecting Rab4a in various cell types.Rab4a is involved in the recycling of endocytosed receptors and plays a critical role in controlling the endocytic pathway. Dysregulation of Rab4a has been linked to various diseases, including cancer and neurodegenerative disorders. By targeting Rab4a with this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these conditions.
Validated for use in Western blot applications, the Rab4a Rabbit Monoclonal Antibody (CAB3979) enables precise detection and analysis of Rab4a protein levels. Its high reactivity with human samples makes it an ideal choice for studies in cell biology, cancer biology, and neuroscience. By understanding the functions of Rab4a, researchers can potentially identify new therapeutic targets for treating diseases associated with aberrant membrane trafficking pathways.
Product Name:
RAB4A Rabbit Monoclonal Antibody
SKU:
CAB3979
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RAB4A (P20338).
This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
5867
Clone Number:
ARC2607
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using RAB4A Rabbit mAb (CAB3979) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
