PTK6 Rabbit Polyclonal Antibody (CAB7497)
- SKU:
- CAB7497
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PTK6 Rabbit Polyclonal Antibody |
SKU: | CAB7497 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 222-451 of human PTK6 (NP_005966.1). |
Sequence: | SRDN LLHQ QMLQ SEIQ AMKK LRHK HILA LYAV VSVG DPVY IITE LMAK GSLL ELLR DSDE KVLP VSEL LDIA WQVA EGMC YLES QNYI HRDL AARN ILVG ENTL CKVG DFGL ARLI KEDV YLSH DHNI PYKW TAPE ALSR GHYS TKSD VWSF GILL HEMF SRGQ VPYP GMSN HEAF LRVD AGYR MPCP LECP PSVH KLML TCWC RDPE QRPC FKAL RERL SSFT SYEN PT |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | BRK; PTK6 |
Positive Sample: | SW480,BT-474,MCF7,A-549,NIH/3T3,Mouse liver,Mouse kidney,Mouse testis,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, Membrane, Nucleus, ruffle. |
Calculated MW: | 52kDa |
Observed MW: | 60kDa |
The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 5753 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |