PSMA Monoclonal Antibody [Pk1H7AT] (CPAB0568)
- SKU:
- CPAB0568
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- Pk1H7AT
- Applications:
- WB
- ELISA
- FC
Description
PSMA Monoclonal Antibody [Pk1H7AT] (CPAB0568)
The PSMA Polyclonal Antibody (CPAB0568) is a vital tool for researchers studying PSMA, a cell surface protein involved in prostate cancer. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the PSMA protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in oncology and cancer research.PSMA, also known as Prostate-Specific Membrane Antigen, is a key target in prostate cancer diagnostics and therapeutics due to its high expression levels in prostate tumor cells.
Understanding the role of PSMA in prostate cancer progression is essential for developing targeted therapies and improving patient outcomes. This antibody provides researchers with a valuable tool to explore the mechanisms of PSMA-mediated tumor growth and metastasis, potentially leading to the development of novel treatment strategies for prostate cancer patients.
Product Name: | PSMA Antibody |
Product Sku: | CPAB0568 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human PSMA mAb is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PSMA amino acids 117-351 purified from Ecoli. |
Clone: | Pk1H7AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA, Flow Cytometry |
Purification Method: | PSMA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG1 |
Background: | PSMA is a cancer antigen that is widely expressed as a noncovalent homodimer on the surface of prostate cancer cells, rather than on normal cells, therefore it is an interesting target to image prostate tissues when being used with radioactive antibodies. PSMA is expressed on the surface of novel blood vessels that nourish a broad range of other solid tumors. PSMA is a type II membrane protein with folate hydrolase activity produced by prostatic epithelium. PSMA expression is found in extraprostatic tissues, including small bowel and brain. |
Synonyms: | PSMA, Prostate Specific Cancer Antigen, PSM, FGCP, FOLH, GCP2, mGCP, GCPII, NAALAD1, NAALAdase, FOLH1, Glutamate carboxypeptidase 2, Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, N-acetylated-alpha-linked acidic dipeptidase I, Pteroylpoly-gamma-glutamate carboxypeptidase, Folylpoly-gamma-glutamate carboxypeptidase, Folate hydrolase 1, Prostate-specific membrane antigen, Cell growth-inhibiting protein 27. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |