PRPF8 Rabbit Polyclonal Antibody (CAB6053)
- SKU:
- CAB6053
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PRPF8 Rabbit Polyclonal Antibody |
SKU: | CAB6053 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PRPF8 (NP_006436.3). |
Sequence: | MAGV FPYR GPGN PVPG PLAP LPDY MSEE KLQE KARK WQQL QAKR YAEK RKFG FVDA QKED MPPE HVRK IIRD HGDM TNRK FRHD KRVY LGAL KYMP HAVL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 |
Synonyms: | PRP8; RP13; HPRP8; PRPC8; SNRNP220; PRPF8 |
Positive Sample: | HeLa,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus speckle. |
Calculated MW: | 274kDa |
Observed MW: | 274kDa |
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
Purification Method: | Affinity purification |
Gene ID: | 10594 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |