The PRAMEF10 Polyclonal Antibody (PACO63703) is a valuable tool for researchers studying PRAMEF10, a protein involved in various cellular processes and potential cancer biomarker. This antibody, produced in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications.PRAMEF10, also known as Preferentially Expressed Antigen in Melanoma Family Member 10, is a member of the PRAME family and has been implicated in tumorigenesis and cancer progression. Its differential expression in cancer cells compared to normal tissues makes it a promising target for cancer research and potential therapeutic interventions.
By using the PRAMEF10 Polyclonal Antibody, researchers can detect and analyze the expression of PRAMEF10 in different cell types, aiding in the understanding of its function in cancer development. This antibody is a valuable tool for studies investigating the role of PRAMEF10 in various cancer types and may provide insights into novel treatment strategies targeting this protein.
Antibody Name:
PRAMEF10 Antibody (PACO63703)
Antibody SKU:
PACO63703
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human PRAME family member 10 protein (1-261AA)
Immunofluorescence staining of K562 cells with PACO63703 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Synonyms:
PRAME family member 10, PRAMEF10
UniProt Protein Function:
PRAMEF10: Belongs to the PRAME family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 1p36.21Molecular Function: retinoic acid receptor bindingBiological Process: negative regulation of retinoic acid receptor signaling pathway; negative regulation of cell differentiation; positive regulation of cell proliferation; negative regulation of transcription, DNA-dependent; negative regulation of apoptosis
