The PPP3CC Polyclonal Antibody (CAB7714) is a valuable tool for researchers studying PPP3CC, a key enzyme involved in calcium signaling pathways. This antibody, produced in rabbits, has high specificity and sensitivity for detecting PPP3CC in human samples, making it ideal for Western blot applications. By binding to the PPP3CC protein, this antibody allows for accurate analysis and detection in a variety of cell types, offering valuable insights into the role of PPP3CC in cellular signaling processes.PPP3CC, also known as calcineurin, is a critical regulator of cellular functions such as gene expression, membrane excitability, and apoptosis.
Dysregulation of PPP3CC has been linked to various diseases, including cancer, neurodegenerative disorders, and immune-related conditions. By studying the function and activity of PPP3CC using this antibody, researchers can gain a better understanding of its role in disease development and progression, paving the way for the development of targeted therapies and treatments.
Product Name:
PPP3CC Rabbit Polyclonal Antibody
SKU:
CAB7714
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 373-512 of human PPP3CC (NP_005596.2).
Sequence:
LISD DEAE GSTT VRKE IIRN KIRA IGKM ARVF SILR QESE SVLT LKGL TPTG TLPL GVLS GGKQ TIET ATVE AVEA REAI RGFS LQHK IRSF EEAR GLDR INER MPPR KDSI HAGG PMKS VTSA HSHA AHRS DQGK KAHS
Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5533
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PPP3CC antibody (CAB7714) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
