The POLR2J Polyclonal Antibody (CAB1843) is a valuable tool for researchers studying the POLR2J protein, a subunit of RNA polymerase II that is essential for transcription. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to the POLR2J protein, it allows for the detection and analysis of this crucial transcription factor in a variety of cell types.The POLR2J protein is involved in the transcription of protein-coding genes and is crucial for the regulation of gene expression. Understanding its function and activity is essential for unraveling the complex mechanisms of transcription and gene regulation.
Researchers studying diseases such as cancer, genetic disorders, and developmental abnormalities will find this antibody invaluable for their work in elucidating the role of POLR2J in these pathological conditions.By utilizing the POLR2J Polyclonal Antibody (CAB1843), researchers can explore the function and regulation of the POLR2J protein, leading to a deeper understanding of transcription processes and potential therapeutic targets for various diseases.
Product Name:
POLR2J Rabbit Polyclonal Antibody
SKU:
CAB1843
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-117 of human POLR2J (NP_006225.1).
This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene exists as a heterodimer with another polymerase subunit; together they form a core subassembly unit of the polymerase. Two similar genes are located nearby on chromosome 7q22.1 and a pseudogene is found on chromosome 7p13.
Purification Method:
Affinity purification
Gene ID:
5439
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using POLR2J antibody (CAB1843) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
