PLOD1 Rabbit Polyclonal Antibody (CAB7919)
- SKU:
- CAB7919
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PLOD1 Rabbit Polyclonal Antibody |
SKU: | CAB7919 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-295 of human PLOD1 (NP_000293.2). |
Sequence: | KGDA KPED NLLV LTVA TKET EGFR RFKR SAQF FNYK IQAL GLGE DWNV EKGT SAGG GQKV RLLK KALE KHAD KEDL VILF ADSY DVLF ASGP RELL KKFR QARS QVVF SAEE LIYP DRRL ETKY PVVS DGKR FLGS GGFI GYAP NLSK LVAE WEGQ DSDS DQLF YTKI FLDP EKRE QINI TLDH RCRI FQNL DGAL DEVV LKFE MGHV RARN LAYD TLPV LIHG NGPT KLQL NYLG NYIP RFWT FETG CTVC DEGL RSLK GIGD EALP TVLV GVFI E |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | LH; LH1; LLH; EDS6; PLOD; EDSKCL1; PLOD1 |
Positive Sample: | HepG2,A-431,U-251MG,Mouse kidney,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Lumenal side, Peripheral membrane protein, Rough endoplasmic reticulum membrane. |
Calculated MW: | 84kDa |
Observed MW: | 84kDa |
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5351 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |