PLCB1 Rabbit Polyclonal Antibody (CAB1971)
- SKU:
- CAB1971
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PLCB1 Rabbit Polyclonal Antibody |
SKU: | CAB1971 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 917-1216 of human PLCB1 (NP_056007.1). |
Sequence: | KSFV KLQK KHYK EMKD LVKR HHKK TTDL IKEH TTKY NEIQ NDYL RRRA ALEK SAKK DSKK KSEP SSPD HGSS TIEQ DLAA LDAE MTQK LIDL KDKQ QQQL LNLR QEQY YSEK YQKR EHIK LLIQ KLTD VAEE CQNN QLKK LKEI CEKE KKEL KKKM DKKR QEKI TEAK SKDK SQME EEKT EMIR SYIQ EVVQ YIKR LEEA QSKR QEKL VEKH KEIR QQIL DEKP KLQV ELEQ EYQD KFKR LPLE ILEF VQEA MKGK ISED SNHG SAPL SLSS DPGK VNHK TPSS EELG GDIP GKEF DTPL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | DEE12; PLC-I; EIEE12; PI-PLC; PLC154; PLCB1A; PLCB1B; PLC-154; PLC-beta-1; PLCB1 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus membrane. |
Calculated MW: | 139kDa |
Observed MW: | 150kDa |
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 23236 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |