The PI4K2A Polyclonal Antibody (CAB16546) is a valuable tool for researchers studying phosphatidylinositol 4-kinase type 2 alpha (PI4K2A), an enzyme involved in the synthesis of phosphoinositides and the regulation of intracellular membrane trafficking. This antibody, raised in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications.PI4K2A plays a crucial role in various cellular processes, including vesicle trafficking, autophagy, and lipid metabolism. Dysregulation of PI4K2A has been linked to diseases such as cancer, neurodegenerative disorders, and infectious diseases.
By targeting and detecting PI4K2A with this antibody, researchers can gain valuable insights into the function and regulation of this enzyme and its potential implications in disease pathology.The PI4K2A Polyclonal Antibody is an essential tool for studies in cell biology, signal transduction, and disease mechanisms, offering researchers the ability to investigate the role of PI4K2A in health and disease and potentially discover novel therapeutic targets for a range of conditions.
Product Name:
PI4K2A Rabbit Polyclonal Antibody
SKU:
CAB16546
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 131-479 of human PI4K2A (NP_060895.1).
Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001 [PubMed 11244087]).
Purification Method:
Affinity purification
Gene ID:
55361
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using PI4K2A Rabbit pAb (CAB16546) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
