The PI15 Polyclonal Antibody (CAB14886) is specifically designed for research involving PI15, a protein that plays a crucial role in regulating cell proliferation and apoptosis. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blotting.PI15 is known to be involved in cellular processes such as cell cycle progression and DNA repair, making it a key target for studies in cancer biology and cell signaling pathways. By binding to the PI15 protein, this antibody enables accurate detection and analysis of PI15 expression in a variety of cell types, providing valuable insights into its function and potential therapeutic applications.
The significance of PI15 in regulating cell growth and survival makes it a promising candidate for research into cancer biology and other diseases characterized by dysregulated cell proliferation. Understanding the molecular mechanisms underlying PI15 activity is essential for developing targeted therapies that can effectively modulate cell growth and promote cellular homeostasis.
Product Name:
PI15 Rabbit Polyclonal Antibody
SKU:
CAB14886
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 61-170 of human PI15 (NP_056970.1).
This gene encodes a trypsin inhibitor. The protein shares similarity to insect venom allergens, mammalian testis-specific proteins and plant pathogenesis-related proteins. It is frequently expressed in human neuroblastoma and glioblastoma cell lines, and thus may play a role in the central nervous system.
Purification Method:
Affinity purification
Gene ID:
51050
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PI15 Rabbit pAb (CAB14886) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
