Phospho-CDK9-T186 Rabbit Polyclonal Antibody (CABP0810)
- SKU:
- CABP0810
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Phospho-CDK9-T186 Rabbit Polyclonal Antibody |
SKU: | CABP0810 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic phosphorylated peptide around T186 of human CDK9 (NP_001252.1). |
Sequence: | RYTN R |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | TAK; C-2k; CTK1; CDC2L4; PITALRE; Phospho-CDK9-T186 |
Positive Sample: | NIH/3T3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, PML body. |
Calculated MW: | 43kDa |
Observed MW: | 43kDa |
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
Purification Method: | Affinity purification |
Gene ID: | 1025 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |