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PGAM2 Monoclonal Antibody [PAT5A7AT] (CPAB0224)

SKU:
CPAB0224
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT5A7AT
Applications:
ELISA
FC
€149
Frequently bought together:

Description

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PGAM2 Monoclonal Antibody [PAT5A7AT] (CPAB0224)

The PGAM2 Polyclonal Antibody (CPAB0224) is a valuable tool for researchers studying PGAM2, a key enzyme involved in glycolysis and energy metabolism. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to the PGAM2 protein, it allows for accurate detection and analysis in a variety of cell types, making it ideal for research in metabolism, cancer biology, and other related fields.PGAM2 is essential for catalyzing the conversion of 3-phosphoglycerate to 2-phosphoglycerate in the glycolytic pathway, a crucial step in energy production.

Dysregulation of PGAM2 has been implicated in various diseases, including cancer, metabolic disorders, and neurological conditions. Investigating the function and regulation of PGAM2 with this antibody can provide valuable insights into these pathologies and potentially lead to the development of targeted therapies.By utilizing the PGAM2 Polyclonal Antibody (CPAB0224), researchers can delve deeper into the roles of PGAM2 in cellular metabolism and disease pathogenesis, paving the way for advancements in personalized medicine and targeted treatment strategies.

Product Name:PGAM2 Antibody
Product Sku:CPAB0224
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PGAM2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PGAM2 protein 1-253 amino acids purified from Ecoli.
Clone:PAT5A7AT.
Reactivity:Human
Applications:ELISA, Flow Cytometry
Purification Method:PGAM2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:Phosphoglycerate mutase 2 (PGAM2) is a member of the phosphoglycerate mutase family. PGAM is a dimeric enzyme which contains in separate tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). PGAM (Phosphoglycerate mutase) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. PGAM2 gene mutations cause muscle phosphoglycerate mutase efficiency, otherwise known as glycogen storage disease X.
Synonyms:Phosphoglycerate mutase 2, BPG-dependent PGAM 2, Muscle-specific phosphoglycerate mutase, Phosphoglycerate mutase isozyme M, PGAM-M, PGAM2, PGAMM, GSD10.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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