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PEBP1 Monoclonal Antibody [PAT4B11AT] (CPAB0670)

SKU:
CPAB0670
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT4B11AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

PEBP1 Monoclonal Antibody [PAT4B11AT] (CPAB0670)

The PEBP1 Polyclonal Antibody (CPAB0670) is a valuable tool for researchers studying the role of PEBP1 in cell signaling pathways and cancer progression. This antibody, generated in rabbits, is highly specific to PEBP1 and has been validated for use in various applications, including Western blotting and immunohistochemistry.PEBP1, also known as phosphatidylethanolamine-binding protein 1, is a key player in cell signaling cascades involved in cell growth, survival, and differentiation.

Dysregulation of PEBP1 has been implicated in many types of cancer, making it a promising target for therapeutic interventions.By using the PEBP1 Polyclonal Antibody, researchers can accurately detect and analyze PEBP1 levels in different cell types and tissues, allowing for a better understanding of its role in disease progression. This antibody is a valuable tool for studies in cancer biology, cell signaling, and drug development aimed at targeting PEBP1 for therapeutic purposes.

Product Name:PEBP1 Antibody
Product Sku:CPAB0670
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PEBP1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PEBP1 protein, 1-187 amino acids purified from Ecoli.
Clone:PAT4B11AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:PEBP1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:PEBP1 (Phosphatidylethanolamine binding protein 1) belongs to the phosphatidylethanolamine-binding protein family and a serine protease inhibitor that inhibits thrombin, neuropsin. PEBP1 plays a key modulatory part in several protein kinase signaling cascades. PKC phosphorylates PEBP1, resulting in the release of Raf-1 and activation of MEK and ERK. PEBP1 is expressed in many tissues and implicated in the regulation of such physiological processes as membrane biosynthesis, spermatogenesis, neural development, and metastasis suppression. PEBP1 binds ATP, opioids and phosphatidylethanolamine, however it has lower affinity for phosphatidylinositol and phosphatidylcholine. PEBP1 may also be involved in the function of the presynaptic cholinergic neurons of the CNS. PEBP1 increases the production of choline acetyltransferase although not acetylcholinesterase. Furtheremore, PEBP1 functions in potentially sequestering toxic compounds, including locostatin which may have harmful effects on cells. Loss of PEBP1 expression may have a significant role as prognostic marker in Gastrointestinal stromal tumors. In addition, PEBP1 is found differentially expressed in the Wernicke's Area from schizophrenia patients. PEBP1 is also, an invasion suppressor protein in nasopharyngeal carcinoma.
Synonyms:Phosphatidylethanolamine-binding protein 1, Prostatic-binding protein, HCNPpp, Neuropolypeptide h3, Raf kinase inhibitor protein, PEBP-1, RKIP, PEBP1, PBP, PEBP, HCNP.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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