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PE/Cyanine7 Anti-Mouse CD18 Antibody [M18/2] (AGEL2744)

SKU:
AGEL2744
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
M18/2
Conjugation:
PE/Cyanine7
$335 - $767
Frequently bought together:

Description

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PE/Cyanine7 Anti-Mouse CD18 Antibody [M18/2]

The PE-Cyanine7 Anti-Mouse CD18 Antibody (M18/2) is a powerful tool for researchers studying immune responses in mice. This antibody is specifically designed to target the CD18 protein, which plays a critical role in mediating cell adhesion and migration in the immune system. By binding to CD18, the antibody enables detection and analysis of this important protein in various cell types, providing valuable insights into immune cell function.CD18 is a key component of integrin receptors on the surface of immune cells, facilitating their ability to interact with other cells and extracellular matrix components. Dysregulation of CD18 expression or function has been implicated in various immune-related disorders, including autoimmune diseases and inflammatory conditions.

By studying CD18 using this antibody, researchers can gain a better understanding of the mechanisms underlying these diseases and potentially identify new therapeutic targets.The PE-Cyanine7 Anti-Mouse CD18 Antibody (M18/2) is highly specific and sensitive, making it a reliable tool for immunology research. Its compatibility with flow cytometry and other analytical techniques allows for accurate quantification and characterization of CD18-expressing cells, aiding in the investigation of immune responses in mouse models. Whether studying inflammation, immune cell trafficking, or immune system dysregulation, this antibody provides a valuable resource for advancing our knowledge of immune function and disease pathology.

Product Title:PE/Cyanine7 Anti-Mouse CD18 Antibody [M18/2]
SKU:AGEL2744
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M18/2
Synonyms:Integrin beta-2;Itgb2;Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta;Complement receptor C3 subunit beta;CD18;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11835
Gene ID:16414
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen.

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