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PE/Cyanine7 Anti-Human/Mouse KLRG-1 Antibody [2F1] (AGEL3133)

SKU:
AGEL3133
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Mouse
Host Species:
Syrian Hamster
Isotype:
Syrian Hamster IgG
Clone:
2F1
Conjugation:
PE/Cyanine7
$263 - $683
Frequently bought together:

Description

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PE/Cyanine7 Anti-Human/Mouse KLRG-1 Antibody [2F1]

The PE-Cyanine7 Anti-Human/Mouse KLRG-1 Antibody (2F1) is a valuable tool for researchers studying immune responses and cell surface molecules involved in immune regulation. This antibody, available from Assay Genie, is specifically designed to detect and bind to the KLRG-1 protein in both human and mouse samples. KLRG-1, also known as killer cell lectin-like receptor subfamily G member 1, is a marker of immune cell subsets and is implicated in the regulation of immune responses. The PE-Cyanine7 Anti-Human/Mouse KLRG-1 Antibody (2F1) is highly reactive and suitable for various applications, including flow cytometry and immunofluorescence.

By targeting KLRG-1, researchers can gain insights into the role of this molecule in immune system modulation, inflammation, and potentially in diseases such as cancer and autoimmune disorders. This antibody is a valuable tool for immunologists and cancer researchers looking to further understand the mechanisms underlying immune responses and develop potential therapeutic interventions.

Product Title:PE/Cyanine7 Anti-Human/Mouse KLRG-1 Antibody [2F1]
SKU:AGEL3133
Size:25µg, 100µg
Clone No:2F1
Synonyms:MAFA; 2F1-Ag;
Host Species:Syrian Hamster
Reactivity:Human;Mouse
Application:FCM
Isotype:Syrian Hamster IgG
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q96E93 O88713
Gene ID:10219,50928
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG25 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

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