The PE-Cyanine5.5 Anti-Rat CD8a Antibody (OX-8) offered by AssayGenie is a powerful tool for researchers studying rat immune responses and T cell biology. This antibody specifically targets the CD8a protein on the surface of rat T cells, allowing for precise detection and analysis in experimental settings. Developed for use in flow cytometry applications, the PE-Cyanine5.5 Anti-Rat CD8a Antibody (OX-8) delivers reliable and consistent results, making it an essential component in immunology research.
The high specificity of this antibody ensures accurate identification of CD8a-positive cells, providing valuable insights into immune cell populations and function.With its superior performance, this antibody is an excellent choice for scientists investigating T cell-mediated immune responses, antigen recognition, and immune system dynamics in rat models. Enhance your research with the exceptional quality and reliability of the PE-Cyanine5.5 Anti-Rat CD8a Antibody (OX-8) from AssayGenie.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P07725
Gene ID:
24930
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).