PDE1B Rabbit Polyclonal Antibody (CAB2102)
- SKU:
- CAB2102
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PDE1B Rabbit Polyclonal Antibody |
SKU: | CAB2102 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 190-536 of human PDE1B (NP_000915.1). |
Sequence: | RHNL ISRF KIPT VFLM SFLD ALET GYGK YKNP YHNQ IHAA DVTQ TVHC FLLR TGMV HCLS EIEL LAII FAAA IHDY EHTG TTNS FHIQ TKSE CAIV YNDR SVLE NHHI SSVF RLMQ DDEM NIFI NLTK DEFV ELRA LVIE MVLA TDMS CHFQ QVKT MKTA LQQL ERID KPKA LSLL LHAA DISH PTKQ WLVH SRWT KALM EEFF RQGD KEAE LGLP FSPL CDRT STLV AQSQ IGFI DFIV EPTF SVLT DVAE KSVQ PLAD EDSK SKNQ PSFQ WRQP SLDV EVGD PNPD VVSF RSTW VKRI QENK QKWK ERAA SGIT NQMS IDEL SPCE EEAP PSPA EDEH NQNG NLD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | PDE1B1; PDES1B; HEL-S-79p; PDE1B |
Positive Sample: | NCI-H460,THP-1,Mouse brain,Mouse spleen,Mouse spinal cord |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 61kDa |
Observed MW: | 59kDa |
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5153 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |