pan-PKC Rabbit Polyclonal Antibody (CAB17922)
- SKU:
- CAB17922
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | pan-PKC Rabbit Polyclonal Antibody |
SKU: | CAB17922 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 572-672 of humanPRKCA (NP_002728.2) |
Sequence: | MTKH PAKR LGCG PEGE RDVR EHAF FRRI DWEK LENR EIQP PFKP KVCG KGAE NFDK FFTR GQPV LTPP DQLV IANI DQSD FEGF SYVN PQFV HPIL QSAV |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | PRKCA/PRKCB/PRKCD/PRKCE/PRKCH/PRKCQ; pan-PKC |
Positive Sample: | HeLa,Jurkat,293T,Mouse brain,Rat brain |
Cellular Localization: | cytoplasm, cytosol, endoplasmic reticulum, extracellular exosome, mitochondrial membrane, mitochondrion, nucleoplasm, perinuclear region of cytoplasm, plasma membrane |
Calculated MW: | 59kDa/67kDa/74- 83kDa |
Observed MW: | 83kDa |
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption.
Purification Method: | Affinity purification |
Gene ID: | 5578/5579/5580/5581/5583/5588 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |