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PAIP2 Monoclonal Antibody [PAT1C12AT] (CPAB0460)

SKU:
CPAB0460
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1C12AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

PAIP2 Monoclonal Antibody [PAT1C12AT] (CPAB0460)

The PAIP2 Polyclonal Antibody (CPAB0460) is a vital tool for researchers studying PAIP2, a protein involved in mRNA translation and stability regulation. This antibody, generated in rabbits, exhibits high specificity towards human samples and has been validated for use in Western blot applications. By targeting the PAIP2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it essential for studies in molecular biology and gene expression research. PAIP2 is known for its role in controlling protein synthesis by interacting with factors that regulate mRNA translation efficiency.

Its involvement in post-transcriptional processes makes it a key player in gene expression regulation. Research on PAIP2 is important for understanding the underlying mechanisms of cellular function and can provide insights into diseases like cancer, neurological disorders, and metabolic diseases. Utilizing the PAIP2 Polyclonal Antibody is crucial for unraveling the intricate pathways that govern gene expression and protein synthesis, paving the way for advancements in biomedicine and therapeutics.

Product Name:PAIP2 Antibody
Product Sku:CPAB0460
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PAIP2 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CMBL 1-127 amino acids purified from Ecoli.
Clone:PAT1C12AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:PAIP2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:PAIP2 has a role as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. PAIP2 inhibitory activity on translation is mediated through its action on PABPC1. PAIP2 displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. PAIP2 association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Synonyms:Poly(A) Binding Protein Interacting Protein 2, PABP- interacting protein 2, HSPC218, PAIP-2, PAIP2A, Polyadenylate-binding protein-interacting protein 2, PAIP2, MGC72018.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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