PADI1/PAD1 Monoclonal Antibody (CAB23951)
- SKU:
- CAB23951
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | PADI1/PAD1 Monoclonal Antibody |
SKU: | CAB23951 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human PADI1/PAD1(NP_037490.2). |
Sequence: | MAPK RVVQ LSLK MPTH AVCV VGVE AHVD IHSD VPKG ANSF RVSG SSGV EVFM VYNR TRVK EPIG KARW PLDT DADM VVSV GTAS KELK DFKV RVSY FGEQ EDQA LGRS VLYL TGVD ISLE VDTG RTGK VKRS QGDK KTWR WGPE GYGA ILLV NCDR DNHR SAEP DLTH SWLM SLAD LQDM SPML LSCN GPDK LFDS HKLV LNVP FSDS KRVR VFCA RGGN SLSD YKQV LGPQ CLSY EVER QPGE QEIK FYVE GLTF PDAD FLGL VSLS VSLV DPGT L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | PADI1; HPAD10; PAD1; PDI; PDI1; peptidyl arginine deiminase 1; PADI1/PAD1 |
Positive Sample: | HaCaT,293T transfected with PADI1/PAD1,Mouse ovary |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 74kDa |
Observed MW: | 75kDa |
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes.
Purification Method: | Affinity purification |
Gene ID: | 29943 |
Clone Number: | ARC61569 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |