The NSUN4 Polyclonal Antibody (CAB14983) is a valuable tool for researchers studying NSUN4, a protein involved in mitochondrial RNA modification. This antibody, produced in rabbits, is highly sensitive and specific for detecting NSUN4 in human samples, making it ideal for use in Western blot applications. By targeting NSUN4, researchers can gain insights into its function in mitochondrial biology and its potential role in disease development.NSUN4 is a mitochondrial RNA methyltransferase that plays a key role in regulating mitochondrial gene expression and protein synthesis. Dysregulation of NSUN4 has been implicated in various diseases, including cancer and mitochondrial disorders.
Understanding the function of NSUN4 and its impact on cellular processes is essential for advancing our knowledge of mitochondrial biology and developing targeted therapies for related conditions.Researchers can rely on the NSUN4 Polyclonal Antibody to effectively detect and analyze NSUN4 expression in different cell types, facilitating detailed investigations into its mechanisms of action. With its high specificity and reliability, this antibody is a valuable resource for studies exploring the molecular mechanisms underlying mitochondrial gene regulation and potential therapeutic targets for diseases associated with NSUN4 dysfunction.
Product Name:
NSUN4 Rabbit Polyclonal Antibody
SKU:
CAB14983
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-290 of human NSUN4 (NP_950245.2).
Enables rRNA (cytosine-C5-)-methyltransferase activity. Involved in rRNA methylation. Part of mitochondrial large ribosomal subunit.
Purification Method:
Affinity purification
Gene ID:
387338
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NSUN4 Rabbit pAb (CAB14983) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
