The NSMAF Polyclonal Antibody (CAB15742) is a valuable tool for researchers studying the NSMAF protein, an integral membrane protein involved in various cellular functions. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for Western blot applications. By binding to the NSMAF protein, this antibody enables the detection and analysis of NSMAF in different cell types, making it perfect for research in cell biology and molecular biology.NSMAF, also known as a regulator of protease activity, plays a crucial role in cellular processes such as protein degradation and intracellular signaling.
It is implicated in diverse physiological and pathological conditions, making it a compelling target for studies on cancer progression, neurodegenerative diseases, and other disorders. Understanding the function of NSMAF is essential for uncovering its potential as a therapeutic target in various diseases and developing new treatment strategies.
Product Name:
NSMAF Rabbit Polyclonal Antibody
SKU:
CAB15742
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NSMAF (NP_003571.2).
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8439
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using NSMAF Rabbit pAb (CAB15742) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 120s.
