NFKBIB Rabbit Polyclonal Antibody (CAB5777)
- SKU:
- CAB5777
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NFKBIB Rabbit Polyclonal Antibody |
SKU: | CAB5777 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-356 of human NFKBIB (NP_002494.2). |
Sequence: | MAGV ACLG KAAD ADEW CDSG LGSL GPDA AAPG GPGL GAEL GPGL SWAP LVFG YVTE DGDT ALHL AVIH QHEP FLDF LLGF SAGT EYMD LQND LGQT ALHL AAIL GETS TVEK LYAA GAGL CVAE RRGH TALH LACR VGAH ACAR ALLQ PRPR RPRE APDT YLAQ GPDR TPDT NHTP VALY PDSD LEKE EEES EEDW KLQL EAEN YEGH TPLH VAVI HKDV EMVR LLRD AGAD LDKP EPTC GRSP LHLA VEAQ AADV LELL LRAG ANPA ARMY GGRT PLGS AMLR PNPI LARL LRAH GAPE PEGE DEKS GPCS SSSD SDSG DEGD EYDD IVVH SSRS QTRL PPTP ASKP LPDD PRPV |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | IKBB; TRIP9; NFKBIB |
Positive Sample: | MCF7,293T,Mouse liver,Mouse skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 38kDa |
Observed MW: | 40-50kDa |
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 4793 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |