NPHP3 Rabbit Polyclonal Antibody (CAB8580)
- SKU:
- CAB8580
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | NPHP3 Rabbit Polyclonal Antibody |
SKU: | CAB8580 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human NPHP3 (NP_694972.3). |
Sequence: | MGTA SSLV SPAG GEVI EDTY GAGG GEAC EIPV EVKP KARL LRNS FRRG AGAA AGAG PGSL PRGV GAGG LLGA SFKS TGSS VPEL EYAA AEYE RLRK EYEI FRVS KNQE LLSM GRRE AKLD TENK RLRA EL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | MKS7; NPH3; RHPD; RHPD1; SLSN3; CFAP31; NPHP3 |
Positive Sample: | 293T,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, cilium. |
Calculated MW: | 151kDa |
Observed MW: | 151kDa |
This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin, it is required for normal ciliary development, and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3, and also with renal-hepatic-pancreatic dysplasia, and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family, member 11) gene.
Purification Method: | Affinity purification |
Gene ID: | 27031 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |