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NDUFA13/GRIM19 Polyclonal Antibody (CAB21531)

SKU:
CAB21531
€129
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Description

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Product Name:NDUFA13/GRIM19 Polyclonal Antibody
SKU:CAB21531
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant Protein corresponding to a sequence within amino acids 52-144 of human NDUFA13/GRIM19 (NP_057049.5).
Sequence:KWNR ERRR LQIE DFEA RIAL LPLL QAET DRRT LQML RENL EEEA IIMK DVPD WKVG ESVF HTTR WVPP LIGE LYGL RTTE EALH ASHG FMWY T
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:B16.6; CDA016; CGI-39; GRIM19; GRIM-19; MC1DN28; NDUFA13/GRIM19
Positive Sample:MCF7,K-562,293T
Conjugate:Unconjugated
Cellular Localization:Matrix side, Mitochondrion inner membrane, Nucleus, Single-pass membrane protein.
Calculated MW:17kDa
Observed MW:15kDa

This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined.

Purification Method:Affinity purification
Gene ID:51079
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using NDUFA13/GRIM19 Rabbit pAb (CAB21531) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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