The MTPAP Polyclonal Antibody (CAB17715) is a valuable tool for researchers studying the mitochondrial poly(A) polymerase (MTPAP) protein. This rabbit polyclonal antibody is highly specific and reactive with human samples, making it an excellent choice for Western blot applications. By binding to the MTPAP protein, this antibody enables the detection and analysis of MTPAP in various cell types, allowing for detailed research in the fields of mitochondrial biology and RNA metabolism.MTPAP is an essential enzyme involved in polyadenylation, a process crucial for the maturation and stability of mitochondrial mRNA.
Dysregulation of MTPAP has been implicated in various diseases, including neurodegenerative disorders and certain types of cancer. By studying the function and expression of MTPAP using this antibody, researchers can gain insights into the role of mitochondrial RNA processing in health and disease.Overall, the MTPAP Polyclonal Antibody (CAB17715) is a reliable tool for investigating the functions of MTPAP in cellular processes, making it a valuable asset for studies in mitochondrial biology, RNA metabolism, and related fields.
Product Name:
MTPAP Rabbit Polyclonal Antibody
SKU:
CAB17715
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 383-582 of human MTPAP (NP_060579.3).
The protein encoded by this gene is a member of the DNA polymerase type-B-like family. This enzyme synthesizes the 3' poly(A) tail of mitochondrial transcripts and plays a role in replication-dependent histone mRNA degradation.
Purification Method:
Affinity purification
Gene ID:
55149
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MTPAP Rabbit pAb (CAB17715) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
