The MS4A12 Polyclonal Antibody (CAB8223) is a valuable tool for researchers studying MS4A12, a membrane protein belonging to the MS4A (membrane-spanning 4-domains subfamily A) family. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the MS4A12 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in immunology and cancer research.
MS4A12 has been implicated in various cellular processes, including cell signaling, proliferation, and differentiation. Its involvement in immune regulation and tumorigenesis highlights its potential as a therapeutic target for diseases such as cancer and autoimmune disorders. By gaining a deeper understanding of the function of MS4A12, researchers can uncover new insights into disease mechanisms and potentially develop novel treatment strategies.
Product Name:
MS4A12 Rabbit Polyclonal Antibody
SKU:
CAB8223
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human MS4A12 (NP_060186.2).
The protein encoded by this gene is a cell surface protein found primarily in the apical membrane of colonocytes. Silencing of this gene in colon cancer cells inhibits the proliferation, cell motility, and chemotactic invasion of cells. This gene is part of a cluster of similar genes found on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
54860
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MS4A12 antibody (CAB8223) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.