The FITC Anti-Human MPO Antibody (ABT-101007) offered by Assay Genie is a high-quality antibody specifically designed for research involving myeloperoxidase (MPO), a key enzyme found in neutrophil granulocytes. This antibody, conjugated with FITC for fluorescence detection, is highly sensitive and specific for human samples, making it ideal for applications such as immunofluorescence and flow cytometry.MPO is an important marker for neutrophil activation and is implicated in various inflammatory conditions, such as cardiovascular diseases, autoimmune disorders, and certain cancers. The FITC Anti-Human MPO Antibody enables precise detection and visualization of MPO within cells or tissues, allowing researchers to study its expression patterns and role in disease pathogenesis.
With its reliable performance and validated specificity, this antibody is a valuable tool for investigations in immunology, inflammation, and related fields.By providing accurate and reproducible results, the FITC Anti-Human MPO Antibody contributes to advancing our understanding of MPO's functions and mechanisms in health and disease. Researchers can leverage this antibody to unravel the complexities of MPO-mediated processes and develop targeted approaches for diagnosing and treating conditions associated with MPO dysregulation.
Product Name:
FITC Anti-Human MPO Antibody [ABT-101007]
Product Code:
AGEL3500
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
ABT-101007
Synonyms:
Myeloperoxidase
Reactivity:
Human
Host Species:
Mouse
Applications:
ICFCM
Isotype:
Mouse IgG1, κ
Isotype Control:
FITC Mouse IgG1, κ Isotype Control [MOPC-21]
Conjugation:
FITC
Applications:
ICFCM
Recommended Dilution:
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage:
Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Fluorescent Label:
FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Shipping:
Biological ice pack at 4°C
Form:
Liquid
Gene ID:
4353
Swissprot:
P05164
Background Information:
Myeloperoxidase (MPO) is a heterotetrameric protein consisting of two 60 kD heavy units and two 12 kD light units. A lysosomal enzyme, MPO is able to catalyze the production of hypochlorous acid, a potent microbicidal agent, from hydrogen peroxide and chloride anion during the neutrophil respiratory burst. MPO is a major enzyme involved in the inflammatory responses of polymorphonuclear leucocytes. MPO is localized to the azurophilic granules of mature granulocytes and monocytes and is also expressed in some acute myeloid leukemia cells.