null

GenieFluor 647 Anti-Mouse CD8a Antibody [53-6.7] (AGEL1345)

SKU:
AGEL1345
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
53-7.6
Conjugation:
AF 647
€209 - €429
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

GenieFluor 647 Anti-Mouse CD8a Antibody [53-6.7]

The Mouse CD8a Monoclonal Antibody (AF647 conjugated) 53-7.6 is a valuable tool for scientists conducting research involving CD8a, a key marker on cytotoxic T cells. This monoclonal antibody, conjugated with AF647 for fluorescent detection, is highly specific to mouse CD8a and is validated for various applications including flow cytometry and immunofluorescence.CD8a is a critical component of the immune system, playing a crucial role in cytotoxic T cell-mediated immune responses against infected or malignant cells. This monoclonal antibody enables precise detection and visualization of CD8a-expressing cells in tissues or cell culture, facilitating accurate identification and analysis in immunology, cancer research, and infectious disease studies.

Researchers can rely on the Mouse CD8a Monoclonal Antibody (AF647 conjugated) 53-7.6 for its sensitivity, specificity, and reproducibility in detecting CD8a expression, providing insights into immune cell populations and their functions. Whether investigating immune responses in infection, autoimmunity, or cancer, this antibody is a valuable asset for understanding the intricacies of the immune system.

Product Title:GenieFluor 647 Anti-Mouse CD8a Antibody [53-6.7]
SKU:AGEL1345
Size:25µg, 100µg
Clone No:53-6.7
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P01731
Gene ID:12525
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

Related Products