The Mouse CD86 Monoclonal Antibody (FITC Conjugated, GL-1, AGEL0544) offered by Assay Genie is a vital tool for research into CD86, a key cell surface protein involved in immune regulation and activation. This monoclonal antibody, engineered for precision and specificity, is designed to target CD86 in mouse samples, enabling accurate detection and analysis in various experimental settings.CD86, also known as B7-2, plays a significant role in T cell co-stimulation and immune response modulation. By binding to CD86, this antibody provides researchers with a reliable means to study the expression and function of CD86 in immunological processes. Whether investigating antigen presentation, T cell activation, or immune cell interactions, the Mouse CD86 Monoclonal Antibody (FITC Conjugated, GL-1, AGEL0544) is a valuable asset in understanding the complexities of the immune system.
Incorporating this antibody into your research arsenal opens up possibilities for exploring immune responses in the context of infection, autoimmunity, transplantation, and vaccine development. Its high specificity and sensitivity make it a trusted tool for immunologists, cell biologists, and researchers working at the forefront of immunology. Enhance your studies and advance your understanding of immune regulation with the Mouse CD86 Monoclonal Antibody from Assay Genie.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P42082
Gene ID:
12524
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.