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MOG Monoclonal Antibody [NYRMOG] (CPAB0479)

SKU:
CPAB0479
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
NYRMOG
Applications:
IP
WB
ELISA
IHC
€660
Frequently bought together:

Description

system_update_alt Datasheet

MOG Monoclonal Antibody [NYRMOG] (CPAB0479)

The MOG Polyclonal Antibody (CPAB0479) is a valuable tool for researchers studying myelin oligodendrocyte glycoprotein (MOG), a key protein involved in the central nervous system and autoimmune disorders such as multiple sclerosis. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting and immunohistochemistry applications. By binding specifically to MOG protein, this antibody enables precise detection and analysis in various cell types, making it an ideal choice for investigations in neuroimmunology and autoimmune disease research.MOG is a critical component of myelin, the protective sheath surrounding nerve fibers, and plays a vital role in maintaining the integrity and function of the nervous system.

Dysregulation of MOG has been implicated in various autoimmune conditions, particularly multiple sclerosis, where the immune system mistakenly attacks myelin, leading to nerve damage and neurological symptoms. Understanding the role of MOG in immune responses and autoimmune pathology is essential for developing targeted therapies and interventions to treat these debilitating conditions. The MOG Polyclonal Antibody provides researchers with a valuable tool for advancing our knowledge of MOG function and its implications in health and disease.

Product Name:MOG Antibody
Product Sku:CPAB0479
Size:500μg
Host Species:mouse
Immunogen:Synthetic pMOG 35-55
Clone:NYRMOG.
Reactivity:Other bodies
Applications:Immuneprecipitation, Western Blot, ELISA, Immunohistochemistry
Purification Method:Ion exchange column.
Isotype:IgG1
Background:MOG is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. MOG is involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified Minor component of the myelin sheath is involved in completion and/or maintenance of the myelin sheath and in cell- cell communication.
Synonyms:MGC26137, MOG, MYELIN-OLIGODENDROCYTE GLYCOPROTEIN.
Storage Buffer:In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

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