MDFI Rabbit Polyclonal Antibody (CAB13709)
- SKU:
- CAB13709
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | MDFI Rabbit Polyclonal Antibody |
SKU: | CAB13709 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human MDFI (NP_005577.1). |
Sequence: | MYQV SGQR PSGC DAPY GAPS AAPG PAQT LSLL PGLE VVTG STHP AEAA PEEG SLEE AATP MPQG NGPG IPQG LDST DLDV PTEA VTCQ PQGN PLGC TPLL PNDS GHPS ELGG TRRA GNGA LGGP KAHR KLQT HPSL ASQG SKKS KSSS KSTT SQIP LQAQ |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | I-MF; I-mfa; MDFI |
Positive Sample: | Mouse heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 25kDa |
Observed MW: | 35kDa |
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
Purification Method: | Affinity purification |
Gene ID: | 4188 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |