MBNL2 Rabbit Polyclonal Antibody (CAB12838)
- SKU:
- CAB12838
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | MBNL2 Rabbit Polyclonal Antibody |
SKU: | CAB12838 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-260 of human MBNL2 (NP_659002.1). |
Sequence: | PPVT VPGS TATQ KLLR TDKL EVCR EFQR GNCA RGET DCRF AHPA DSTM IDTS DNTV TVCM DYIK GRCM REKC KYFH PPAH LQAK IKAA QHQA NQAA VAAQ A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MBLL; MBLL39; PRO2032; MBNL2 |
Positive Sample: | A-549,HeLa,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 41kDa |
Observed MW: | 39kDa |
This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.
Purification Method: | Affinity purification |
Gene ID: | 10150 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |