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MAFK Monoclonal Antibody [PAT2F7A] (CPAB0574)

SKU:
CPAB0574
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT2F7A
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

MAFK Monoclonal Antibody [PAT2F7A] (CPAB0574)

The MAFK Polyclonal Antibody (CPAB0574) is a vital tool for researchers studying the MAFK protein, which belongs to the basic leucine zipper (bZIP) transcription factor family. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in a variety of applications, including Western blot and immunohistochemistry.MAFK is involved in various cellular processes, including regulation of gene expression, cell differentiation, and response to oxidative stress. Its role in promoting cancer progression and metastasis has garnered significant interest in the fields of oncology and molecular biology.

The MAFK Polyclonal Antibody enables precise detection and analysis of MAFK expression in different cell types, facilitating in-depth research into its function and potential as a therapeutic target.By understanding the molecular mechanisms mediated by MAFK, researchers can uncover new insights into disease pathways and potentially develop targeted treatments for cancer and other conditions influenced by MAFK activity. The MAFK Polyclonal Antibody offers a reliable tool for investigating the functions of this critical transcription factor and its implications in various biological processes.

Product Name:MAFK Antibody
Product Sku:CPAB0574
Size:5μg
Host Species:Mouse
Immunogen:Anti-human MAFK mAb, clone PAT2F7A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human MAFK protein 1-156 amino acids  purified from Ecoli.
Clone:PAT2F7A.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:MAFK antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2a
Background:MAFK is a member of the bZIP family and Maf subfamily. Members from Maf family of basic region/leucine zipper (bZIP) transcription factors influence transcription in a positive or negative way, depending on their protein associate and the context of the target promoter. Small Mafs act as transcriptional repressors when they dimerize among themselves. Yet, they seem to function as transcriptional activators by dimerizing with other basic-zipper proteins and employing them to specific DNA-binding sites.
Synonyms:NFE2U, P18, Erythroid transcription factor NF-E2 p18 subunit, MAFK, Transcription factor MafK.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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