The LAMP1 Polyclonal Antibody (CAB21771) is a valuable tool for research involving LAMP1, a protein involved in lysosomal biogenesis and autophagy. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the LAMP1 protein, this antibody allows for the detection and analysis of LAMP1 in various cell types, making it ideal for studies in cell biology and disease research.LAMP1, also known as lysosomal-associated membrane protein 1, plays a crucial role in maintaining lysosomal function and promoting autophagy, a process essential for cellular homeostasis and the removal of damaged organelles.
Dysregulation of LAMP1 has been implicated in various diseases, including neurodegenerative disorders and cancer. By studying the function of LAMP1, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify novel therapeutic targets.
Product Name:
LAMP1 Polyclonal Antibody
SKU:
CAB21771
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 81-259 of human LAMP1 (NP_005552.3).
Cell membrane, Endosome membrane, Late endosome, Lysosome membrane, Single-pass type I membrane protein.
Calculated MW:
45kDa
Observed MW:
90-120kDa
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.
Purification Method:
Affinity purification
Gene ID:
3916
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using LAMP1 Rabbit pAb (CAB21771) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
