The KRTAP13-1 Polyclonal Antibody (PACO37806) is a vital tool for researchers studying keratin-associated protein 13-1 (KRTAP13-1), a protein involved in hair formation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in various applications, including Western blotting.KRTAP13-1 is a key player in the process of hair development, making it a target of interest in studies related to hair biology and dermatology. By specifically binding to KRTAP13-1, this antibody enables accurate detection and analysis of the protein in different cell types, making it an excellent choice for research in these fields.
The role of KRTAP13-1 in hair growth regulation and maintenance highlights its potential significance in understanding conditions such as hair disorders and alopecia. Research utilizing this antibody can provide valuable insights into the mechanisms underlying hair formation and offer potential avenues for developing therapies to address related issues.
Antibody Name:
KRTAP13-1 Antibody (PACO37806)
Antibody SKU:
PACO37806
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Keratin-associated protein 13-1 protein (1-172AA)
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Synonyms:
Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1), KRTAP13-1, KAP13.1 KRTAP13.1
UniProt Protein Function:
KRTAP13-1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the PMG family.Chromosomal Location of Human Ortholog: 21q22.1Cellular Component: intermediate filament
UniProt Protein Details:
NCBI Summary:
Hair keratins and hair keratin-associated proteins (KAPs), such as KRTAP13-1, are the main structural proteins of hair fibers (Rogers et al., 2002 [PubMed 12359730]).[supplied by OMIM, Mar 2008]
