[KO Validated] CD2BP2 Rabbit Polyclonal Antibody (CAB19891)
- SKU:
- CAB19891
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | [KO Validated] CD2BP2 Rabbit Polyclonal Antibody |
SKU: | CAB19891 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human CD2BP2 (NP_006101.1). |
Sequence: | MPKR KVTF QGVG DEED EDEI IVPK KKLV DPVA GSGG PGSR FKGK HSLD SDEE EDDD DGGS SKYD ILAS EDVE GQEA ATLP SEGG VRIT PFNL QEEM EEGH FDAD GNYF LNRD AQIR DSWL DNID WVKI RERP PGQR QASD SEEE DSLG QTSM SAQA LLEG LLEL LLPR ETVA GALR RLGA RGGG KGRK GPGQ PSSP QRLD RLSG LADQ MVAR GNLG VYQE TRER LAMR LKGL GCQT LGPH NPTP PPSL DMFA EELA EEEL ETPT PTQR GEAE SRGD GLVD VMWE YKWE NTGD AELY GPFT SAQM QTWV SEGY FPDG VYCR KLDP PGGQ FYNS KRID FDLY T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LIN1; Snu40; FWP010; U5-52K; PPP1R59; P2 |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 38kDa |
Observed MW: | 50kDa |
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 10421 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |