The CD2BP2 Polyclonal Antibody (CAB19891) is a valuable tool for researchers studying CD2BP2, a protein involved in immune regulation and cell signaling pathways. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is specifically validated for use in Western blot applications.CD2BP2 is a multifunctional protein that plays a key role in immune response modulation, making it a target of interest in studies related to immunology and cancer research. By binding to the CD2BP2 protein, this antibody enables researchers to detect and analyze its expression in various cell types, providing insight into its functions and interactions within the immune system.
Furthermore, CD2BP2 has been implicated in various diseases, including cancer and autoimmune disorders, highlighting its importance in understanding and targeting these conditions. By utilizing the CD2BP2 Polyclonal Antibody in research, scientists can uncover valuable information that may lead to the development of innovative therapeutic strategies for treating these diseases.
Product Name:
[KO Validated] CD2BP2 Rabbit Polyclonal Antibody
SKU:
CAB19891
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human CD2BP2 (NP_006101.1).
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
Purification Method:
Affinity purification
Gene ID:
10421
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and CD2BP2 knockout (KO) 293T cells, using [KO Validated] CD2BP2 Rabbit pAb (CAB19891) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
