KEAP1 Polyclonal Antibody (CAB21724)
- SKU:
- CAB21724
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- IF
Frequently bought together:
Description
Product Name: | KEAP1 Polyclonal Antibody |
SKU: | CAB21724 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 320-510 of human KEAP1 (NP_036421.2). |
Sequence: | RAPK VGRL IYTA GGYF RQSL SYLE AYNP SDGT WLRL ADLQ VPRS GLAG CVVG GLLY AVGG RNNS PDGN TDSS ALDC YNPM TNQW SPCA PMSV PRNR IGVG VIDG HIYA VGGS HGCI HHNS VERY EPER DEWH LVAP MLTR RIGV GVAV LNRL LYAV GGFD GTNR LNSA ECYY PERN EWRM ITAM NTIR SGA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | INrf2; KLHL19; P1 |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 70kDa |
Observed MW: | 60-64kDa |
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 9817 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |