The ITPR1 Polyclonal Antibody (PAC064283) is a valuable tool for research involving ITPR1, a key protein involved in calcium signaling and neuronal function. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards ITPR1 in human samples, making it ideal for use in Western blot applications. By binding to ITPR1, researchers can effectively study its expression and function in various cell types, particularly in the fields of neuroscience and neurodegenerative diseases.ITPR1, also known as inositol 1,4,5-trisphosphate receptor type 1, plays a crucial role in intracellular calcium release and signaling pathways in neurons.
Dysregulation of ITPR1 has been implicated in various neurological disorders, including spinocerebellar ataxia and Alzheimer's disease. Understanding the role of ITPR1 in calcium signaling and neuronal function is essential for developing targeted therapies for these conditions and advancing our knowledge of neuronal communication and synaptic plasticity.
Antibody Name:
ITPRIPL2 Antibody (PACO64283)
Antibody SKU:
PACO64283
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:1000-1:5000, IF:1:100-1:500
Species Reactivity:
Human
Immunogen:
Recombinant Human Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2 protein (75-288AA)
Western Blot. Positive WB detected in: MCF-7 whole cell lysate. All lanes: ITPRIPL2 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 59 kDa. Observed band size: 59 kDa.
Immunofluorescence staining of Hela cells with PACO64283 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
