CD11b/ITGAM Rabbit Polyclonal Antibody (CAB1581)
- SKU:
- CAB1581
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CD11b/ITGAM Rabbit Polyclonal Antibody |
SKU: | CAB1581 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 145-340 of CD11b/ITGAM (NP_000623.2). |
Sequence: | PQED SDIA FLID GSGS IIPH DFRR MKEF VSTV MEQL KKSK TLFS LMQY SEEF RIHF TFKE FQNN PNPR SLVK PITQ LLGR THTA TGIR KVVR ELFN ITNG ARKN AFKI LVVI TDGE KFGD PLGY EDVI PEAD REGV IRYV IGVG DAFR SEKS RQEL NTIA SKPP RDHV FQVN NFEA LKTI QNQL REKI FAIE GTQT |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; CD11b/ITGAM |
Positive Sample: | THP-1,U-937,Mouse lung,Mouse brain,Mouse spleen,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 127kDa |
Observed MW: | 170kDa |
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3684 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |