IMPDH1 Rabbit Polyclonal Antibody (CAB16899)
- SKU:
- CAB16899
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | IMPDH1 Rabbit Polyclonal Antibody |
SKU: | CAB16899 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 434-563 of human IMPDH1 (NP_899066.1). |
Sequence: | MMGS LLAA TTEA PGEY FFSD GVRL KKYR GMGS LDAM EKSS SSQK RYFS EGDK VKIA QGVS GSIQ DKGS IQKF VPYL IAGI QHGC QDIG ARSL SVLR SMMY SGEL KFEK RTMS AQIE GGVH GLHS YEKR LY |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | IMPD; RP10; IMPD1; LCA11; IMPDH-I; sWSS2608; IMPDH1 |
Positive Sample: | BT-474,HT-29,Mouse pancreas |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 55kDa |
Observed MW: | 55kDa |
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3614 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |