IL1RA Rabbit Polyclonal Antibody (CAB2088)
- SKU:
- CAB2088
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | IL1RA Rabbit Polyclonal Antibody |
SKU: | CAB2088 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-177 of human IL1RA (NP_776214.1). |
Sequence: | ICRP SGRK SSKM QAFR IWDV NQKT FYLR NNQL VAGY LQGP NVNL EEKI DVVP IEPH ALFL GIHG GKMC LSCV KSGD ETRL QLEA VNIT DLSE NRKQ DKRF AFIR SDSG PTTS FESA ACPG WFLC TAME ADQP VSLT NMPD EGVM VTKF YFQE DE |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA |
Positive Sample: | A-431 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Secreted. |
Calculated MW: | 20kDa |
Observed MW: | 18kDa |
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Purification Method: | Affinity purification |
Gene ID: | 3557 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |