Human UFC1 Recombinant Protein (RPPB2398)
- SKU:
- RPPB2398
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9Y3C8
- Research Area:
- Enzymes
Frequently bought together:
Description
| Product Name: | Human UFC1 Recombinant Protein |
| Product Code: | RPPB2398 |
| Size: | 20µg |
| Species: | Human |
| Target: | UFC1 |
| Synonyms: | Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1, UFC1, CGI-126, HSPC155. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | UFC1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT. |
| Stability: | UFC1 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MADEATRRVV SEIPVLKTNA GPRDRELWVQ RLKEEYQSLI RYVENNKNAD NDWFRLESNK EGTRWFGKCW YIHDLLKYEF DIEFDIPITY PTTAPEIAVP ELDGKTAKMY RGGKICLTDH FKPLWARNVP KFGLAHLMAL GLGPWLAVEI PDLIQKGVIQ HKEKCNQ |
UFC1 is a member of the ubiquitin-conjugating enzyme family. UFC1 is an E2-like conjugating enzyme for ubiquitin-fold modifier-1. UFM1 is activated by UBA5 (a novel E1-like enzyme) by forming a high-energy thioester bond. Activated UFM1 is subsequently transferred to its cognate E2-like enzyme, UFC1, in a similar thioester linkage.
UFC1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 187 amino acids (1-167 a.a.) and having a molecular mass of 21.6kDa.UFC1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. |
| NCBI Summary: | UFC1 is an E2-like conjugating enzyme for ubiquitin-fold modifier-1 (UFM1; MIM 610553) (Komatsu et al., 2004 [PubMed 15071506]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9Y3C8 |
| NCBI GenInfo Identifier: | 156416000 |
| NCBI Gene ID: | 51506 |
| NCBI Accession: | NP_057490 |
| UniProt Secondary Accession: | Q9Y3C8,Q549X0, Q5VTX1, Q9BS96, Q9P009, A8K9R1, D3DVF9 |
| UniProt Related Accession: | Q9Y3C8 |
| Molecular Weight: | 21.6 kDa (187aa), confirmed by MALDI-TOF |
| NCBI Full Name: | ubiquitin-fold modifier-conjugating enzyme 1 |
| NCBI Synonym Full Names: | ubiquitin-fold modifier conjugating enzyme 1 |
| NCBI Official Symbol: | UFC1�� |
| NCBI Official Synonym Symbols: | HSPC155�� |
| NCBI Protein Information: | ubiquitin-fold modifier-conjugating enzyme 1 |
| UniProt Protein Name: | Ubiquitin-fold modifier-conjugating enzyme 1 |
| UniProt Gene Name: | UFC1�� |
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