Nanodisc Human TRPM1 Protein (HDFP669)
- SKU:
- HDFP669
- Size:
- 10μg
- Target:
- TRPM1
- Tag:
- C-Flag Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Frequently bought together:
Description
| Product Name: | Nanodisc Human TRPM1 Protein |
| SKU: | HDFP669 |
| Size: | 10μg |
| Target: | TRPM1 |
| Tag: | C-Flag Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | CSNB1C, LTRPC1, MLSN1 |
| Protein Families: | Ion Channels: Transient receptor potential. |
| Protein Description: | Human TRPM1 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length TRPM1 protein has a MW of 182.2kDa |
This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
| Uniprot ID: | Q7Z4N2 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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